1. ASTHMA: asthma may be worsened by NSAIDs
2. IMPAIRED LIVER FUNCTION
3. IMPAIRED RENAL(kidney) FUNCTION
4. HISTORY OF GASTRO-INTESTINAL PROBLEMS such as bleeding ulcer, Ulcerative Colitis.
5. HISTORY OF HYPERSENSITIVITY (such as rashes due to NSAIDs)
6. BLEEDING DISORDERS
7. CARDIAC IMPAIRMENT
CONTRA-INDICATION: active peptic ulcer
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